Quarantine all cattle that are new to the property (including those returning from agistment), as many will carry resistant worms. Treating new cattle on arrival with a quarantine drench is good biosecurity and will reduce the chance and number of resistant worms being introduced onto your property.
Quarantine treatments should ideally contain as many active ingredients as possible, best done by using multi-combination drenches.
Do not mix different drenches together unless the label states you can, or under veterinary advice. This is because different products may be chemically incompatible and could harm treated animals. It is safer to use a commercially-prepared combination product.
After drenching, ideally hold the treated cattle in yards. Alternatively they can be put to graze a paddock that has recently held cattle. These strategies ensure that any resistant worms surviving the quarantine treatment will either die by drying out in the yards, or be diluted by susceptible worms in the paddock (see the section on refugia).
Monitoring the new cattle through WECs will confirm the quarantine drenching has been successful.