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Home Chemical Groups and Actives Salicylanilides (SC)

Salicylanilides (SC)

What do they treat?

√ Liver fluke

  • Oxyclozanide is currently only available in Australia as a mixture with levamisole

Note:  √ Toxic to many aquatic organisms.

How can they be administered?

A variety of application methods for administering pesticide products to cattle are in use. Currently there is one available for this chemical:

√ Oral

  • Always check label information as dose rates for cattle are often higher than those for sheep.


Reported in:  √ Liver fluke

What is resistance?


  • Salicylanilides are generally regarded as compounds of low-toxicity but can cause eye and skin irritation in some people.

Everyone working in the rural industry has a ‘duty of care’; a legal obligation to provide a safe workplace for everyone on the property.


  • Always check the product label before use for specific withholding periods (WHP) and export slaughter interval (ESI) periods. Current ESI periods can be confirmed on the APVMA website.

Withholding periods are mandatory with all registered veterinary products used to treat animals for internal and external parasites.

Types of salicylanilide

A guide to the actives available and the pests affected is in Table 1. See the ParaBoss Products Search Guide (covering WormBoss, TickBoss, LiceBoss and FlyBoss) for the appropriate formulation and application method for your target pest. Note combinations and mixtures of actives may improve treatment efficacy.

Table 1. Salicylanilide group – their active, combinations and mixtures and a summary of the targeted parasites for which formulations are registered for. Boxed check marks indicate the pest targeted by multiple actives.

Pests targeted (may vary with formulation)
Worms Flies Ticks Lice Mites
Round-worm Tape worm Liver fluke
Mixtures (multiple targets)
Oxyclozanide and levamisole

What are they?

Salicylanilides are narrow-spectrum anthelmintics.

They were first introduced in the 1960s and 70s.

How do they work?

Salicylanilides disrupt the energy producing mitochondria within the parasites cells impairing mobility.

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